This article targets to examine the impact of cultural values- power distance and uncertainty avoidance on consumer attitude towards global brands and how this consumer attitude further influences materialism and cosmopolitanism. Also the mediating impact of consumer attitude is tested. An aggregate of usable 455 questionnaires were collected from consumers from numerous Indian cities through the mall intercept approach. Structural Equation modelling was applied to test the hypothesized model. Results suggested a positive association between cultural values (uncertainty avoidance and power distance) and consumer attitudes towards global brands. In line with the hypothesis, consumer attitude was positively linked to consumer domain values- materialism and cosmopolitanism. Results revealed a partial mediating effect of consumer attitudes in paths involving materialism. While full mediating effect of consumer attitudes was found in paths involving cosmopolitanism.