This paper has no intention of "carrying out an experiment to prove or disprove the necessary and sufficient condition for the effect of the multimedia programme on potential changes on spoken vocabulary acquisition in students with autism; therefore it is neither a programme evaluation nor an implementation study. However, although the purpose of this study is to investigate the potential progress in spoken vocabulary acquisition or learning in subjects with autism, it is not a phonetic study or a speech assessment in the sense that professional speech therapists (SP) or experts have been doing, namely assessment on lexicon, semantics, syntactic, and pragmatics, and measurement on utterances, as has been done in previous studies. Following SP's techniques and processes, as well as making use of SP's evaluation tools, is thus not recommended in this situation. The validity of the self-developed multimedia learning programme was, however, increased via the inclusion of a variety of language evaluation instruments and a language scheme utilised in a well-established local special school different than the target school. In addition, a previously developed multimedia programme" was utilised during the pilot stage.