The purpose of this study was to identify anthropometric and somatotypological markers in mature age men signaling an increased possibility of osteochondrosis developing in lumbosacral spine. The method of complex anthropometry and somatotyping was used to study the physical status of 102 Kyrgyz men of the 2nd period of adulthood, who are in medical institutions in Osh, Kyrgyzstan. The comparison group consisted of 300 men of this age without somatic diseases conditional norm. The entire complex of anatomical and anthropometric examinations performed according to generally accepted ethical standards, with informed consent of all examined patients. Statistical data processing includes calculation of arithmetic mean indicators and their errors. Differences assessed by Student's method at p<0.05. Results showed that among men in main group, abdominal somatotype representatives are 54 % which is 1.8 times more (p<0.05), and the muscular somatotype is 12 %, on the contrary, is 1.8 times less (p<0.05) than in control group. The relative representation of men with chest somatotype is 8 % and with indeterminate 26 %, suffering from lumbosacral sciatica, almost does not differ from the control. Markers of a high probability of the formation of this nosological form are, according to our data, an increase in the thickness of the skinfat folds of the chest, back, abdomen, shoulder, thigh (by 1.1–3.3 times, compared with the control, p<0.05). The physical status of men suffering from lumbosacral sciatica is also characterized by an increased content of the body fat component, an increase in weight and body mass index, regardless of their somatotypological characteristics (p<0.05). Obtained data undoubtedly have not only theoretical, but also practical significance.