Aquatic plants are noteworthy forms of plant-life and they are commonly found to have specialized footing in pond ecosystem. However, they can be even found in other water bodies like lakes, channels, swamps, and rivers. These plants have been considered unproductive and impractical for long and have been measured more as of weeds. Although the aquatic conditions of India are ironic sources of various of such plant species, studies pertaining to reckon their medicinal uses are scanty. Yet, some recent studies reported various pharmacological properties such as antiulcer, antiemetic, astringent, anthelmintic, ant dysentery, diuretic, anti-inflammatory, antioxidant, hypercholesterolemia, antipyretic, hepatoprotective, hypoglycaemic, antifungal, of many of these aquatic plant species. Hence, it was thought worthy to provide an overall therapeutic potential of these aquatic plants. In this regard, this review highlights different prospective therapeutic potential of commonly available aquatic plants of different regions of India, that will help readers and researchers interested to peruse research in evaluating the therapeutic effectives of extracts or isolated components of these plant species to establish their applicability in field of medicine.