Manuscript Title:

VITAMIN C; PHARMACOKINETICS AND ITS PROPHYLACTIC APPROACH TO COMBAT ANTIMICROBIAL DISEASES

Author:

SANABIL YAQOOB, BISMILLAH MUBEEN, MIAN SHAMAS MURTAZA, NIDA FIRDOUS, AYSHA IMTIAZ, YINKA AFUSAT AREGBE, YONGKUN MA

DOI Number:

DOI:10.5281/zenodo.10812698

Published : 2024-03-10

About the author(s)

1. SANABIL YAQOOB - School of Food Science and Biological Engineering, Jiangsu University, Zhenjiang, China, Department of Food Science and Technology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan.
2. BISMILLAH MUBEEN - School of Food Science and Biological Engineering, Jiangsu University, Zhenjiang, China.
3. MIAN SHAMAS MURTAZA - School of Food Science and Biological Engineering, Jiangsu University, Zhenjiang, China, Department of Food Science and Technology, MNS-University of Agriculture, Multan, Pakistan.
4. NIDA FIRDOUS - Department of Food Science and Technology, MNS-University of Agriculture, Multan, Pakistan.
5. AYSHA IMTIAZ - National Institute of Food Science and Technology, University of Agriculture, Faisalabad Pakistan.
6. YINKA AFUSAT AREGBE - School of Food Science and Biological Engineering, Jiangsu University, Zhenjiang, China.
7. YONGKUN MA - Professor, School of Food Science and Biological Engineering, Jiangsu University, Zhenjiang, China.

Full Text : PDF

Abstract

The role of vitamin C in the prevention and treatment of numerous illnesses and disorders has been documented for millennia. It is quite useful in the fight against microbiological infections. It has a wideranging effect on microorganisms. It combats harmful germs found in food. It has the ability to stimulate lymphocytes and natural killer cells, thus aiding in the battle against microorganism-caused disorders. As a result, it has pleiotropic physiological effects linked to a variety of disorders, including the common cold, sepsis, acute respiratory distress syndrome (ARDS), and, most importantly, COVID-19. It has a complex pharmacokinetic profile. Absorption and elimination are highly dose-dependent and primarily regulated by a collection of saturable sodium-dependent vitamin C transporters (SVCTs). Genetic polymorphisms, environmental influences, and lifestyle decisions all influence its homeostasis. Vitamin C dietary dose depends on different age groups, health condition and lifestyle of anybody.


Keywords

Ascorbic Acid (ASC), Vitamin C, Pharmacokinetic, Sepsis, Antimicrobial, Antiviral, Antioxidant, Common Cold, COVID-19.