World health organization reported that 80% people in the world used the indigenous plants for their primary health care. The present study was designed to manuscript traditional knowledge of indigenous peoples, who are applying the herbal medicines in the Taunsa and Fortmonroe Punjab Pakistan. Environmental characteristics, responsible for plant distribution in Fortmonru and Taunsa region seem to be salinity, organic matter and ionic concentration Affiliation of vegetation with soil forms remained predictable for regulate the record operative considerations accountable in the supply of plants categories in Fortmonru and Taunsa region... The relationship of assured plant species to firm soil forms was mutually representing the impact of chemical conformation of the soils. The outcome revealed noticeable significant associations among soil appearances and plant species. Demographic. Features, edaphic characteristics and percentage of plant part used show significant use of traditional knowledge in Taunsa and Fortmonroe Punjab Pakistan. An ethnobiological study of important plants of Fortmonru and Taunsa, Punjab, Pakistan was carried out.103 species were designated as medicinally significant plants that belongs to 46 different families. Leaves constitute 69% followed by seed 44%, fruit35%, root31%, flower 25%, stem14%, milky latex 3%, rhizome and pulp 1% both. Fort Monroe and Taunsa are two region of south Punjab where no study was carried out regarding the ethnobiology. Plant as a whole and its parts have been reported utilized by local people hakims and practitioners as a medicine. The information concerning traditional use of plants was together from local communities through knowledgeable approval semi- structured interviews from 184 key informants. The extract of these plants parts used for the treatment of lungs, heart, gastrointestinal and dermalogical disorders, liver, kidney, gallbladder problems, pulmonary and respiratory diseases. Quantitative analysis of the indigenous medicinal plants was carried out by calculating UV value and Rfc value of each plant that provide the basic health information about important medicinal plants of Fortmonru and Taunsa, Punjab, Pakistan. Phytochemical analysis and pharmacological activities will be perform for some selected plants on the basis their medicinal importance and utilization.