Klebsiella spp. are Gram negative, non-motile, usually capsulated rods. They are frequently found inthe large intestine but are also present in soil and water. These organisms are usually opportunistic pathogens that cause nosocomial infections, especially urinary tract and respiratory tract infections.Klebsiella species often produces beta-lactamases and are resistant to ampicillin. Cephalosporins andaminoglycosides are used to treat Klebsiella infections. Some Klebsiella strains show multiple drugresistance and are an important cause of hospital acquired infections. The aim of this study is to determine the prevalence and antimicrobial susceptibility patterns of Klebsiella species. Purely isolated colonies of Klebsiella spp. were obtained, biochemical tests and gram staining wereperformed for identification. Isolated colonies will be streaked on Mueller Hinton agar plate for antibiotic sensitivity testing. The Antibiotic susceptibility test will be determined according to the Clinical and Laboratory Standards Institute (CLSI) interpretive criteria. An Antibiotic impregnated disk will be placed on MH agar and inoculated with the test bacterium. A clear zone or ring will be formed around an antibiotic disk after incubation if the agent inhibits bacterial growth. According toantibiogram results of 143 isolates of K. pneumoniae, the highest antibiotic resistance was related toamoxicillin-clavulanate (98%), cefexime (96.70%) and cefotaxime (97%) and 96.60% isolates weresusceptible to colistin. Isolates also show susceptibility to gentamicin (82%), amikacin (78.10%), tigecycline (75.50%), sulzone (69.20%), imipenem (56%). It also shows resistance to cotrimoxazole(89%), ceftriaxone (87.49%), ciprofloxacin (79%), ceftazidime (86.30%).