Background: Globally burns are a serious public health problem. It is a common type of traumatic injury and accounting for 96% of fatal fire-related burns occur in low and middle-income countries. Aim: To evaluate the effect of a modified dressing technique on wound status and pain perception among patients with burn injuries. Design: pre/posttest nonequivalent control group quasi experimental design was utilized. Setting: Burn department in one of teaching hospitals of Cairo University-Egypt. Sample: A convenient sample of 60 adult patients having 2nd degree of burn superficial deep partial thickness burn. Tools: Three tools were utilized to gather data (1) Personal and Medical Data Form, (II) Bates-Jensen Wound Assessment tool and (III) Short Form of the McGill Pain Questionnaire. Results: Results supported the stated research hypotheses. There were a highly statistically significant differences between the study and control groups regarding total mean scores of wound status parameters after implementing a modified dressing techniques (f =16.17;Pvalue =0.00*).In relation to pain perception: a highly statistically significant differences were found between the study and control groups after implementing a modified dressing technique regarding to pain rating index (PRI) at the end of 1st week (X2= 11.8; P= 0.003*) and 2nd week (X2= 17.8, P= 0.00*). As regards Visual Analogy Scale (VAS) at the end of the 1st and 2ndweek before and after implementing modified dressing technique (t=0,000*; P=1.000), (t=2.502; P=0.015*), (t=2.2474; P=0.016*) and (t=4.127; P=0.000*) respectively. While, there were statistically significant differences were found between the study and control groups concerning total mean of pain present index (PPI) after implementing a modified dressing technique at the end of 1st and 2nd week (t=5.3; P=0.02*) and (t=6.2; P=0.01*) respectively. Conclusion: The current study concluded that implementing a modified dressing technique by using normal saline0.09% in burn wound cleansing may be of great value in improving patients wound status and reducing pain perception compared with tape water. Recommendation: To validate and generalize the results, the study should be repeated on a larger sample in different settings. Using modified dressing techniques as a new approach for Burn dressing.