The study is set out to determine the efficacy of psycho-religious counseling in enhancing decision-making abilities among high school girls in Amman, Jordan. In the study, a semi-experimental design was adopted that included a sample size of 100 female students taught at Princess Basma Comprehensive Secondary School for girls in Amman, Jordan. These students were divided into a group that was supposed to be exposed to psycho-religious counseling and another that was not exposed to it. The decision-making ability was assessed with a specially designed scale for this purpose, its correctness was checked, and the reliability was tested. This was an intervention for a religious counseling program with 15 sessions, 45 minutes each, conducted over a month and a half. The results were greatly significant to enhance decision making skills among female students in the experimental group compared with the control group, with statistical analysis giving evidence as to the effectiveness of the program. The results of the study proved that psycho-religious counseling considerably improves an individual's decision-making ability and enhances the psychological and mental health of the students. Many recommendations have been put forward for opening similar counseling programs at other educational stages and including the development of decision-making ability through religious and psychological counseling.