Background: Diabetes related complications typically developed gradually, particularly when diabetes mellitus (DM) is poorly managed. Among these, diabetic foot problems represent a significant public health problem, that contribute to the global burden of disability and substantially reduce quality of foot health. Audiovisual foot and ankle exercise is a non-pharmacological therapy for patients with DM, had positive effects on foot health and overall mobility. Aim: To evaluate the effect of audiovisual foot- ankle exercise on foot sensation and lower extremities circulation among patients with diabetes mellitus. Design: A pretest-posttest, nonequivalent, control group quasi-experimental design. Sample: A purposive sample of 60 adult male and female patients with type 2 DM, were selected from 8/2023 to 2/2024 and divided into study and control groups. Setting: The study was conducted at medical outpatient clinics in National Institute of Diabetes and Endocrinology in Cairo, Egypt. Tools: Personal and Medical Background Information Form (PMBIF), 10-g Monofilament of Semmes-Weinstein (SWM) Test and Ankle Brachial Index Scale (ABI). Results: The mean age of the study and control groups were 47.13±10.29 and 51.77±8.07 years respectively. Females represented approximately three fourth in both groups. A statistically significant differences in foot sensation between the study and control groups in the post test (2) was found. Concerning ABI; there were statistically significant differences between the study and control groups in the post-test (1) and post-test (2). Conclusion: Performing audiovisual foot ankle exercise as a nonpharmacological therapy for patients with DM is effective to improve foot sensation and lower extremities circulation. Recommendation: Incorporating audiovisual foot ankle exercise into the routine care of patients with DM is recommended to support foot health and prevent complications.