The construction and infrastructure sector, responsible for 40% of global resource consumption and 30% of waste generation, urgently requires circular economy (CE) integration to mitigate environmental degradation, this systematic review, compliant with PRISMA 2020 guidelines, synthesizes 61 peer reviewed studies (2013–2023) to analyze CE-driven resource flow optimization across infrastructure project lifecycles, findings reveal that CE implementation reduces material waste by up to 50% and carbon emissions by 35% when applied holistically from design to end-of-life phases, key strategies include design for disassembly (DfD), industrial symbiosis, and digital tools like BIM and IoT, barriers include fragmented supply chains and underutilized flow-efficiency metrics, the study proposes a lifecycle resource flow model to standardize CE integration, supporting global "Net Zero Emission" targets, statistical validation confirms that policy incentives and circular financing elevate project sustainability by 45%.