This study aims to examine variation in the use of marketing mix strategies across developed and emerging markets using a descriptive meta-analytic approach. A systematic review of 50 prior studies was conducted, covering the four core elements of the marketing mix: product, pricing, distribution, and promotion. The findings reveal that developed markets tend to adopt innovation-driven product strategies, value-based pricing (≈68%), integrated omnichannel distribution (100%), and long-term digital promotion strategies. In contrast, emerging markets rely more heavily on product adaptation, penetration pricing (≈approximately 75%), intensive distribution (100%), and sales promotion activities (≈approximately 68%), reflecting greater price sensitivity and institutional constraints. However, the results indicate that this traditional dichotomy is increasingly diminishing, particularly after 2020, due to the acceleration of digital transformation. The study identifies the emergence of hybrid strategies that combine standardization and adaptation, as well as traditional and digital channels. Notably, digitalization emerges as a critical determinant shaping marketing strategies, often exceeding the influence of market classification. From a theoretical perspective, the study contributes by integrating marketing theory that effective marketing strategies depend on firms’ ability to adapt to contextual factors such as digital maturity, industry characteristics, and temporal dynamics. In practice, the findings highlight the importance for firms of designing flexible, data-driven marketing strategies tailored to the specific economic and digital conditions of each market. Overall, this study provides a comprehensive framework for understanding how marketing mix strategies evolve across different market contexts in an increasingly digital and dynamic environment. From Saudi Perspective, the study contributes to Saudi Vision 2030 by providing a context-driven framework that aligns marketing strategies with digital transformation and economic diversification goals. It demonstrates how integrating innovation, value-based approaches, and data-driven marketing enhances efficiency, competitiveness, and long-term value creation. Accordingly, the findings support sustainable growth in the Kingdom by enabling the development of resilient, knowledge-based market systems grounded in digital capabilities.