Objectives: To evaluate and compare the effect of different beverages (cola, orange juice, apple juice) on color stability of PMMA endocrown and preformed zirconia crowns as restorations of pulpotomized primary molars. Materials and Methods: The study included unidentified fifty-six freshly extracted human mandibular second primary molars underwent pulpotomy procedure. Teeth were randomly subdivided into two main groups according to the type of coronal restoration each comprising twenty-eight specimens: CAD/CAM Milled PMMA endocrown, and preformed zirconia crown. Afterward, specimens in each group were randomly subdivided into four subgroups seven on each according to the different treatment modalities. Specimens were subjected to thermocycling and pH cycling to evaluate color stability using reflective spectrophotometer. The collected data were examined for outliers and tested for normality using Shapiro-Wilk and ANOVA test at 0.05 significance level. Results: There was highly statistically significant difference between the four subgroups regarding color stability in PMMA endocrown and zirconia crown with the highest impact for cola (p < 0.001*) and lowest impact for artificial saliva (p < 0.001*). Intergroup comparison demonstrated highly statistically significant differences between both groups in all beverages (p < 0.001*). Conclusion: PMMA endocrown revealed noteworthy changes under oral conditions, while zirconia crowns remained more stable, highlighting the need for selection of good material for durable, minimally invasive pediatric restoration and limitation of the consumption of carbonated and fruit juices for durable, minimally invasive pediatric restorations.