This study explored the challenges of the 52 pre-service teachers in lesson planning and ICT integration in the 21st century classroom of Iloilo Science and Technology University- Miagao Campus, Miagao, Iloilo. The challenges encountered in Lesson Planning were: poor articulation of instructional objectives, failure to address and integrate the three key components of lesson plan Learning Objectives, Learning activities and Assessment. As to the ICT Integration, unavailability of personal laptops and equipment for academic purposes, lack of ICT competencies for both the preservice and Cooperating teachers, and limited Internet accessibility were the challenges encountered. Pre-service Teachers’ Workshop was the output of the study. FGD and document analysis were administered in data gathering while Thematic Analysis was employed in the data interpretation. It is recommended that the preservice teachers may be provided assistance such as mentoring, remediation, training workshops and in scheduling common planning periods to plan lessons and ICT Integration.