Background: Phototherapy is the primary mode of treatment of physiological jaundice but it has many adverse reactions. Foot reflexology and body massage therapy have recognized as novel approaches to neonatal care that improve the management of neonatal illnesses and overall health. Aim: To evaluate the effect of foot reflexology and body massage on selected outcomes among neonates undergoing phototherapy. Methods: A single-blinded randomized controlled trial design was utilized on a purposive sample of one hundred and five full-term neonates with physiological jaundice from Neonatal Intensive Care Unit at EL Monira Pediatric Hospital that is affiliated to Cairo University from April 2023 to June 2024. The sample randomly assigned to three equal groups, namely foot reflexology, body massage and control using block randomization. Tools: two tools were utilized: neonatal characteristics and neonates' clinical outcomes. Foot reflexology and body massage were performed once a day for fifteen minutes for five consecutive days. Transcutaneous bilirubin and serum bilirubin levels, defecation frequency and phototherapy duration were recorded daily through the intervention five days. Results: Before intervention there were no significant differences in the mean of transcutaneous and serum bilirubin levels among the three study groups, while it decreased significantly in reflexology and massage groups compared to control after intervention. Defecation frequency increased significantly for all neonates in the three study groups from the second day. Total days mean on phototherapy decreased significantly in reflexology and massage groups compared to control group. Conclusion: Neonates undergoing phototherapy who received foot reflexology or body massage had lower bilirubin levels, more defecation frequency and shorter duration on phototherapy than who not receive. Foot reflexology and body massage had the same effect on bilirubin levels, and duration on phototherapy. Recommendation: Foot reflexology and body massage must be taken into consideration as a complementary modality that should be incorporated into nursing care because it is a safe, cost-efficient and well tolerated by neonates with physiological jaundice undergoing phototherapy.